Graduate MCO

Student Publications

Publications 2008

46 publications listed for 2008

  1. Freudiger, CW, Min, W, Saar, BG, Lu, S, Holtom, GR, He, C, Tsai, JC, Kang, JX, andXie, XS. (2008) Label-free biomedical imaging with high sensitivity by stimulated Raman scattering microscopy. Science, 322(5909):1857-61. PMID: 19095943PMC3576036
    X. Sunney Xie Lab (CCB)
  2. Di Giorgio, FP, Boulting, GL, Bobrowicz, S, and Eggan, KC. (2008) Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation. Cell Stem Cell, 3(6):637-48. PMID: 19041780
    Kevin Eggan Lab (SCRB)
  3. Maherali, N, and Hochedlinger, K. (2008) Guidelines and techniques for the generation of induced pluripotent stem cells. Cell Stem Cell, 3(6):595-605. PMID:19041776
    Konrad Hochedlinger Lab (HSCI)
  4. Mugford, JW, Sipilä, P, McMahon, JA, and McMahon, AP. (2008) Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidney. Dev. Biol., 324(1):88-98. PMID:18835385 PMC2642884
    Andrew McMahon Lab (MCB)
  5. Lu, X, McDonald, SM, Tortorici, MA, Tao, YJ, Vasquez-Del Carpio, R, Nibert, ML, Patton, JT, and Harrison, SC. (2008) Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1. Structure, 16(11):1678-88. PMID: 19000820 PMC2602806
    Stephen Harrison Lab (HMS)
  6. Nolan, ME, Aranda, V, Lee, S, Lakshmi, B,Basu, S, Allred, DC, and Muthuswamy, SK. (2008) The polarity protein Par6 induces cell proliferation and is overexpressed in breast cancer. Cancer Res., 68(20):8201-9. PMID: 18922891 PMC2948755
    Tom Maniatis Lab (MCB)
    X. Sunney Xie Lab (CCB)
  7. Kummer, DA, Chain, WJ, Morales, MR, Quiroga, O, and Myers, AG. (2008) Stereocontrolled alkylative construction of quaternary carbon centers. J. Am. Chem. Soc., 130(40):13231-3. PMID: 18788739PMC2666470
    Andrew Myers Lab (CCB)
  8. Banse, AV, Chastanet, A, Rahn-Lee, L, Hobbs, EC, and Losick, R. (2008) Parallel pathways of repression and antirepression governing the transition to stationary phase in Bacillus subtilis. Proc. Natl. Acad. Sci. U.S.A., 105(40):15547-52. PMID: 18840696PMC2563134
    Richard Losick Lab (MCB)
  9. Maherali, N, Ahfeldt, T, Rigamonti, A, Utikal, J, Cowan, C, and Hochedlinger, K. (2008) A high-efficiency system for the generation and study of human induced pluripotent stem cells. Cell Stem Cell, 3(3):340-5. PMID: 18786420
    Konrad Hochedlinger Lab (HSCI)
  10. Park, IH, Arora, N, Huo, H, Maherali, N, Ahfeldt, T, Shimamura, A, Lensch, MW, Cowan, C, Hochedlinger, K, and Daley, GQ. (2008) Disease-specific induced pluripotent stem cells. Cell, 134(5):877-86. PMID:18691744 PMC2633781
    Konrad Hochedlinger Lab (HSCI)
  11. Zhang, XY, Chen, VL, Rosen, MS, Blair, ER,Lone, AM, and Bishop, AC. (2008) Allele-specific inhibition of divergent protein tyrosine phosphatases with a single small molecule. Bioorg. Med. Chem., 16(17):8090-7. PMID: 18678493PMC2561268
    Alan Saghatelian Lab (CCB)
  12. Kaushansky, A, Gordus, A, Budnik, BA, Lane, WS, Rush, J, and MacBeath, G. (2008) System-wide investigation of ErbB4 reveals 19 sites of Tyr phosphorylation that are unusually selective in their recruitment properties. Chem. Biol., 15(8):808-17. PMID: 18721752 PMC2606095
    Gavin MacBeath Lab (HMS SYSBIO)
  13. Kain, J, He, GG, and Losick, R. (2008) Polar localization and compartmentalization of ClpP proteases during growth and sporulation in Bacillus subtilis. J. Bacteriol., 190(20):6749-57. PMID: 18689476 PMC2566194
    Richard Losick Lab (MCB)
  14. Kobayashi, A, Valerius, MT, Mugford, JW, Carroll, TJ, Self, M, Oliver, G, andMcMahon, AP. (2008) Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development. Cell Stem Cell, 3(2):169-81. PMID: 18682239PMC2561900
    Andrew McMahon Lab (MCB)
  15. Mugford, JW, Sipilä, P, Kobayashi, A, Behringer, RR, and McMahon, AP. (2008) Hoxd11 specifies a program of metanephric kidney development within the intermediate mesoderm of the mouse embryo. Dev. Biol., 319(2):396-405. PMID:18485340 PMC2580739
    Andrew McMahon Lab (MCB)
  16. Lei, M, and Erikson, RL. (2008) Plk1 depletion in nontransformed diploid cells activates the DNA-damage checkpoint. Oncogene, 27(28):3935-43. PMID:18297112
    Raymond Erikson Lab (MCB)
  17. Lee, S, Radom, CT, and Verdine, GL. (2008) Trapping and structural elucidation of a very advanced intermediate in the lesion-extrusion pathway of hOGG1. J. Am. Chem. Soc., 130(25):7784-5. PMID:18507380 PMC2878488
    Gregory Verdine Lab (SCRB)
  18. Datta, SS, Strachan, DR, Khamis, SM, and Johnson, AT. (2008) Crystallographic etching of few-layer graphene. Nano Lett., 8(7):1912-5. PMID: 18570483
    David Weitz Lab (SEAS)
  19. Gladyshev, EA, Meselson, M, and Arkhipova, IR. (2008) Massive horizontal gene transfer in bdelloid rotifers. Science, 320(5880):1210-3. PMID: 18511688
    Matthew Meselson Lab (MCB)
  20. Procko, E, and Gaudet, R. (2008) Functionally important interactions between the nucleotide-binding domains of an antigenic peptide transporter. Biochemistry, 47(21):5699-708. PMID:18452308
    Rachelle Gaudet Lab (MCB)
  21. Vegas, AJ, Fuller, JH, and Koehler, AN. (2008) Small-molecule microarrays as tools in ligand discovery. Chem Soc Rev, 37(7):1385-94. PMID: 18568164PMC2688956
    Stuart Schreiber Lab (CCB)
  22. Tsiairis, CD, and McMahon, AP. (2008) Disp1 regulates growth of mammalian long bones through the control of Ihh distribution. Dev. Biol., 317(2):480-5. PMID: 18395198 PMC2430380
    Andrew McMahon Lab (MCB)
  23. Abbondanzieri, EA, Bokinsky, G, Rausch, JW, Zhang, JX, Le Grice, SF, and Zhuang, X. (2008) Dynamic binding orientations direct activity of HIV reverse transcriptase. Nature, 453(7192):184-9. PMID: 18464735PMC2655135
    Xiaowei Zhuang Lab (CCB)
  24. Bruzewicz, DA, Reches, M, andWhitesides, GM. (2008) Low-cost printing of poly(dimethylsiloxane) barriers to define microchannels in paper. Anal. Chem., 80(9):3387-92. PMID: 18333627
    George Whitesides Lab (CCB)
  25. Chen, JR, Chang, BH, Allen, JE, Stiffler, MA, and MacBeath, G. (2008) Predicting PDZ domain-peptide interactions from primary sequences. Nat. Biotechnol., 26(9):1041-5. PMID: 18711339PMC2655215
    Gavin MacBeath Lab (HMS SYSBIO)
  26. Kleiner, RE, Brudno, Y, Birnbaum, ME, and Liu, DR. (2008) DNA-templated polymerization of side-chain-functionalized peptide nucleic acid aldehydes. J. Am. Chem. Soc., 130(14):4646-59. PMID:18341334 PMC2748799
    David Liu Lab (CCB)
  27. Kaushansky, A, Gordus, A, Chang, B, Rush, J, and MacBeath, G. (2008) A quantitative study of the recruitment potential of all intracellular tyrosine residues on EGFR, FGFR1 and IGF1R. Mol Biosyst, 4(6):643-53. PMID: 18493663PMC2811368
    Gavin MacBeath Lab (HMS SYSBIO)
  28. Wagner, BK, Carrinski, HA, Ahn, YH, Kim, YK, Gilbert, TJ, Fomina, DA, Schreiber, SL, Chang, YT, and Clemons, PA. (2008) Small-molecule fluorophores to detect cell-state switching in the context of high-throughput screening. J. Am. Chem. Soc., 130(13):4208-9. PMID: 18327938
    Stuart Schreiber Lab (CCB)
  29. Gladyshev, E, and Meselson, M. (2008) Extreme resistance of bdelloid rotifers to ionizing radiation. Proc. Natl. Acad. Sci. U.S.A., 105(13):5139-44. PMID: 18362355PMC2278216
    Matthew Meselson Lab (MCB)
  30. Bruzewicz, DA, McGuigan, AP, andWhitesides, GM. (2008) Fabrication of a modular tissue construct in a microfluidic chip. Lab Chip, 8(5):663-71. PMID:18432334
    George Whitesides Lab (CCB)
  31. Humphreys, BD, Valerius, MT, Kobayashi, A, Mugford, JW, Soeung, S, Duffield, JS,McMahon, AP, and Bonventre, JV. (2008) Intrinsic epithelial cells repair the kidney after injury. Cell Stem Cell, 2(3):284-91. PMID: 18371453
    Andrew McMahon Lab (MCB)
  32. Stadtfeld, M, Maherali, N, Breault, DT, and Hochedlinger, K. (2008) Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse. Cell Stem Cell, 2(3):230-40. PMID: 18371448PMC3538379
    Konrad Hochedlinger Lab (HSCI)
  33. Li, C, Ge, B, Nicotra, M, Stern, JN, Kopcow, HD, Chen, X, and Strominger, JL. (2008) JNK MAP kinase activation is required for MTOC and granule polarization in NKG2D-mediated NK cell cytotoxicity. Proc. Natl. Acad. Sci. U.S.A., 105(8):3017-22. PMID:18287025 PMC2268577
    Jack Strominger Lab (MCB)
  34. Handler, AA, Lim, JE, and Losick, R. (2008) Peptide inhibitor of cytokinesis during sporulation in Bacillus subtilis. Mol. Microbiol., 68(3):588-99. PMID: 18284588PMC2603569
    Richard Losick Lab (MCB)
  35. Krzewski, K, Chen, X, and Strominger, JL. (2008) WIP is essential for lytic granule polarization and NK cell cytotoxicity. Proc. Natl. Acad. Sci. U.S.A., 105(7):2568-73. PMID: 18258743 PMC2268177
    Jack Strominger Lab (MCB)
  36. Chamberlain, CE, Jeong, J, Guo, C, Allen, BL, and McMahon, AP. (2008) Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning. Development, 135(6):1097-106. PMID:18272593
    Andrew McMahon Lab (MCB)
  37. Strachan, DR, Johnston, DE, Guiton, BS,Datta, SS, Davies, PK, Bonnell, DA, and Johnson, AT. (2008) Real-time TEM imaging of the formation of crystalline nanoscale gaps. Phys. Rev. Lett., 100(5):056805. PMID: 18352410
    David Weitz Lab (SEAS)
  38. Anderson, WJ, Zhou, Q, Alcalde, V, Kaneko, OF, Blank, LJ, Sherwood, RI, Guseh, JS, Rajagopal, J, and Melton, DA. (2008) Genetic targeting of the endoderm with claudin-6CreER. Dev. Dyn., 237(2):504-12. PMID: 18213590 PMC2665265
    Doug Melton Lab (SCRB)
  39. Lang, GI, and Murray, AW. (2008) Estimating the per-base-pair mutation rate in the yeast Saccharomyces cerevisiae. Genetics, 178(1):67-82. PMID: 18202359PMC2206112
    Andrew Murray Lab (MCB)
  40. Pakotiprapha, D, Inuzuka, Y, Bowman, BR, Moolenaar, GF, Goosen, N, Jeruzalmi, D, and Verdine, GL. (2008) Crystal structure of Bacillus stearothermophilus UvrA provides insight into ATP-modulated dimerization, UvrB interaction, and DNA binding. Mol. Cell, 29(1):122-33. PMID:18158267 PMC2692698
    Gregory Verdine Lab (SCRB)
  41. Leung, Y, Ally, S, and Goldberg, MB. (2008) Bacterial actin assembly requires toca-1 to relieve N-wasp autoinhibition. Cell Host Microbe, 3(1):39-47. PMID: 18191793PMC2234351
    Marcia Goldberg Lab (HMS MICROBIO)
  42. McGuigan, AP, Bruzewicz, DA, Glavan, A, Butte, MJ, Butte, M, and Whitesides, GM. (2008) Cell encapsulation in sub-mm sized gel modules using replica molding. PLoS ONE, 3(5):e2258. PMID: 18493609PMC2376064
    George Whitesides Lab (CCB)
  43. Choi, PS, Zakhary, L, Choi, WY, Caron, S, Alvarez-Saavedra, E, Miska, EA, McManus, M, Harfe, B, Giraldez, AJ, Horvitz, HR, Schier, AF, and Dulac, C. (2008) Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron, 57(1):41-55. PMID:18184563 PMC2204047
    Catherine Dulac Lab (MCB)
  44. Orger, MB, Kampff, AR, Severi, KE, Bollmann, JH, and Engert, F. (2008) Control of visually guided behavior by distinct populations of spinal projection neurons. Nat. Neurosci., 11(3):327-33. PMID: 18264094 PMC2894808
    Florian Engert Lab (MCB)
  45. Muecke, M, Samuels, M, Davey, M, andJeruzalmi, D. (2008) Preparation of multimilligram quantities of large, linear DNA molecules for structural studies. Structure, 16(6):837-41. PMID: 18547516
    David Jeruzalmi Lab (MCB)
  46. Yanai, I, Baugh, LR, Smith, JJ, Roehrig, C,Shen-Orr, SS, Claggett, JM, Hill, AA, Slonim, DK, and Hunter, CP. (2008) Pairing of competitive and topologically distinct regulatory modules enhances patterned gene expression. Mol. Syst. Biol., 4:163. PMID: 18277379 PMC2267734
    Craig Hunter Lab (MCB)