News from 2025

Decoding Learning: How Cues and Rewards Shape Behavior and Dopamine Signals

A new study from Naoshige Uchida's MCB lab provides new insight into how the brain processes contingency during associative learning. Published in Nature Neuroscience (PDF), the study demonstrates…

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Call for Nominations: 2025 MCB Mentorship Award

The MCB Community Task Force (CTF) is excited to announce that nominations for the 2025 MCB Mentorship Award are now open! This annual award recognizes individuals within the…

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New Deep Learning Framework Reveals Hidden Structure in Neural Activity

Understanding how neurons encode information is one of the most pressing challenges in neuroscience. A new study from a multidisciplinary team including MCB researchers and those from the…

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MCB to Host 2025 Prather Lectures Featuring Feng Zhang

This year, MCB will host the annual John M. Prather Lectures in Biology, a series of three talks inspired by a bequest to Harvard by the 19th-century Harvard-trained…

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Avoid or ignore? How the Brain Copes with a Potential Threat

When faced with an unfamiliar threat, animals must make split-second decisions: should they flee to avoid potential harm or push forward in pursuit of a reward? This fundamental…

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The Development of Instincts at the Single Cell Level

A new study from the Dulac Lab explores how one small brain region called the preoptic area (POA) of the hypothalamus changes through early life in mice. Though…

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Dulac Lab Identifies “Loneliness” Neurons in the Hypothalamus

Loneliness is encoded in the brain in a way that closely resembles the neural architectures governing drives like thirst and hunger, researchers from the Dulac Lab report. A…

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Innate or Earned? Rethinking the Role of Activity in Brain Development

Sixty years ago, Harvard scientists David Hubel and Torsten Wiesel famously showed that altering visual input in young cats irreversibly changed the organization of neurons in the visual…

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Harvard’s Program for Scientifically Inspired Leadership Bridges Educational Cultures

Each January, while many students enjoy a well-earned winter break, a select group of Harvard undergraduates embarks on a journey that transcends traditional learning. Founded by Dominic Mao,…

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How Brains (and AI) Use Variability in Rewards to Bolster Learning

In domains as diverse as mastering video games, controlling robotic limbs, and finetuning ChatGPT, a family of approaches known collectively as “reinforcement learning” (RL) has revolutionized the field…

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