Lab Overview
Most of our work aims at defining the molecular rules that shape and retain neuronal diversity in the cerebral cortex; understanding how pyramidal neuron diversity affects the behavior of other neurons and glia to build functional cortical circuits; and exploring the boundaries of the stability of postmitotic neuron identity in vivo.
While our work is rooted in development, we are also interested in understanding and modeling complex human cortical pathology, focusing on the development of new high-throughput in vitro models of human cortical development and neurodevelopmental disease using 3D cerebral organoids.