When selecting fluorescent proteins (FPs), it is standard practice to select FPs with the highest in vitro brightness. However, it is well-known that in vitro brightness does not…
Tag: Philippe Cluzel
DECIPHERING A REGULATORY CODE WITHIN THE GENETIC CODE [CLUZEL LAB]
Arvind Subramaniam The genetic code is degenerate because most of the amino acids used in protein synthesis are encoded by multiple nucleotide triplets, or codons. The amino acid…
PREDICTING BACTERIA’S RESPONSE TO MULTIDRUG TREATMENT [CLUZEL LAB]
Severe microbial infections, such as tuberculosis and MRSA, often require treatment with three (or more) drugs. Multidrug therapies are currently discovered by empirically testing large numbers of potentially…
HOW TO INFER CELLULAR RESPONSE TO A SMALL STIMULUS FROM BEHAVIORAL VARIABILITY BEFORE STIMULUS IN BACTERIA
Heungwon Park Over the last decade, there has been a series of remarkable studies dealing with the characterization of noise in gene regulatory networks and signaling pathways. However,…
PHILIPPE CLUZEL’S RANDOM WALK FROM PHYSICS TO BIOLOGY
Philippe Cluzel On a bookshelf in his office, MCB Professor of Molecular and Cellular Biology Philippe Cluzel keeps several beautifully bound leather tomes from his parents’ antiquarian bookstore…