(l to r) Sophie de Buyl, Shu-Wen Teng, Jeffrey R. Moffitt, and Shankar Mukherji with Nikhil Living organisms tightly coordinate their physiology with the day and night cycle.…
Erin O'Shea (l) and Andrian Gutu The day-night cycle is the most predictable environmental variation on Earth. Many organisms, ranging from bacteria to humans have evolved endogenous time-keeping…
Nan Hao (l) and Erin O'Shea Living organisms respond to external cues and initiate appropriate physiological responses through activation of transcription factors, which regulate expression of target genes.…
Erin O'Shea The prestigious Howard Hughes Medical Institute has named Erin K. O’Shea as Vice-President for Science and Chief Scientific Officer. O’Shea is the director of the Harvard…
Last year, we wrote about MCB Professor Erin O'Shea’s championship dog, Zambo, and his victory at the Universal Sieger World Championships in Austria where he received the world’s…
Erin K. O'Shea and Zambo Erin O'Shea is a world leader in studies of gene regulation, but a world champion? That’s a title reserved for her German…
Erin K. O'Shea and Xu Zhou Gene expression is controlled by a class of proteins called transcription factors. These proteins usually bind to short 6-8 base pair DNA…
Michael J. Rust and Erin K. O'Shea Circadian clocks are biological oscillators that help organisms keep track of the time of the day and coordinate their behavior with…
Andrew Capaldi and Erin O'Shea The gene expression program in a cell is set in response to the level, timing and combination of hundreds of developmental and environmental…
Erin O'Shea, and Harold Kim One of the main challenges in the postgenomic era is to understand how genetic information is translated into quantitative transcriptional output. Transcription factors…
