(l to r) Jeff Lichtman, Josh Morgan, Jose Conchello, Daniel Berger, and Richard Schalek This paper describes a suite of automated technologies designed to probe the structure of…
Jeff Lichtman (l) and Doug Richardson The Harvard Center for Biological Imaging (HCBI) recently celebrated its five year anniversary. A central pillar in its mandate is to ensure…
We have suggested that chromosomes should be viewed as macroscopic mechanical objects whose functions are governed by accumulation, release and redistribution of mechanical stress. We have proposed specifically…
The aim of developmental neurobiology is to learn how the nervous system is built, and to find the developmental anomalies that are thought to underlie some brain diseases. …
(l to r) Anna Puszynska, Joseph Piechura, and Erin O'Shea (not shown Joseph Markson) Organisms from humans to bacteria utilize endogenous timing mechanisms called circadian clocks to coordinate…
(l to r) Carl Wu, Vu Nguyen, Debbie Wei, Anand Ranjan, and Andres Leschziner Genome packaging is a universal process in eukaryotes. In the smallest repeating unit of…
(l to r) Guillaume Witz, Mara Prentiss, Nancy Kleckner, Beth Weiner, and Jay K. Fisher The E. coli chromosome is a single circular unit which, if stretched out,…
(L to R) Sirui Zou, Bret Redwine, Andres Leschziner, Rogelio Hernandez-Lopez, and Samara Reck-Peterson, front row Locksley Walking takes an enormous amount of coordination. As your leading foot…
A fundamental question in developmental biology is how multi-potent cells choose a fate. While we know a lot about how cell states are maintained through growing amounts of…
Meiosis is a modified cellular program by which a single diploid cell gives rise to haploid gametes (e.g. sperm and egg). To this end, DNA replication is followed…
