I am teaching a new class starting this semester (Fall 2022): Applied Physics 242 / MCB 161 “Introduction to Single-Molecule Biophysics”.
The course will cover the structure of biological molecules and cells, their energetics, and single-molecule measurements, focusing primarily on single-molecule FRET and single-molecule localization microscopy (SMLM) methods.
The goal for the course is to ultimately benefit the research of enrolled students. By the end of the course, the students will be able to assess whether single-molecule approaches would be beneficial for their work and which approach would be most suitable, will know key literature, will have an understanding of design considerations of single-molecule instruments and experiments, and will have the necessary skills to analyze single-molecule data.
Lectures will be on Mondays and Wednesday 10:30-11:45 am and Section will be on Fridays at the same time, both in Maxwell Dworkin 221.
The course is open to graduate students and advances undergraduates across disciplines including biology, chemistry, physics, and engineering. College-level physics (at the level of Applied Physics 50a and 50b or above) and college-level chemistry and biology (at the level of Life Sciences 1A or Life and Physical Sciences A) will be useful.
Basic knowledge in one of the general-purpose programming languages such as Matlab or Python is required.