Our brains generally represent the outside world using ordered maps. For example, neighboring points in visual space activate neighboring points on the retina, and this relation is preserved…
Many regions of the brain are organized in such a way that they form an ordered representation of our sensory experiences. Similar physical stimuli –nearby points of light…
(left panel) Monocular retinal innervation in a normal larval zebrafish. The right optic tectal lobe receives input solely from the contralateral (red) retina. (right panel) Following rewiring, the…
Some of the authors (left to right): Corey M McCann, Juan Carlos Tapia, and Jeff W Lichtman Image shows submandibular ganglion neurons (blue) that express Cyan Fluorescent Protein…
The human brain represents approximately 2% of the total body weight, but accounts for about 20% of the energy consumed. Functional hyperemia (local increases in blood flow triggered…
In a behaving animal, the brain processes information from sensory inputs, and communicates its intentions to muscles via the pattern of activity in descending projection neurons. In vertebrates,…
Modern genetics textbooks highlight the concept of the ‘central dogma’ which states that DNA is transcribed into messenger RNA (mRNA) and that mRNA is subsequently translated into proteins. …
Perhaps you have had the experience of walking into a new environment, such as a Moroccan bazaar or a Chinese supermarket for the first time, and being struck…
This illustration is a surface representation of the TRPV1ankyrin repeat structure (in green) with a bound ATP molecule (multicolor sticks) on a background of capsaicin-laden red pepper flakes.…
Sleep is one of the major remaining mysteries in biology. Although we spend a third of our life asleep, it is still unclear why we sleep and how…
