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The O’Shea lab is interested in systems and molecular analysis of signal transduction and transcriptional regulation. Many of our studies make use of two model systems in budding yeast: (1) the Pho pathway, which allows cells to sense and respond to changes in environmental levels of inorganic phosphate, and (2) the Hog pathway, involved in responding to osmotic stress.


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Access the Yeast GFP Fusion Localization Database here: http://yeastgfp.ucsf.edu

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